The U.S. Environmental Protection Agency (EPA) has developed screening levels for the chemicals of concern detected.  The results of the Annette Islands Study were compared to these EPA screening levels, and when measured levels were greater than the screening level, an estimate of risk was calculated. The only EPA screening levels that contaminant levels in this study came close to were those for cancer risk.  Incidentally, cancer risk is what the Community was most concerned about.

The risk calculations were based on the conservative assumption that a person consumed an 8-ounce serving of the seafood species in question every day for 70 years.  The conclusion of this preliminary risk assessment was that all the results are with the "safe range" defined by EPA.  (This "safe range" allows a risk increase between one in 10,000 and one in 1,000,000.)

ATSDR then developed a health consultation for the Community, and confirmed that the seafood of the Annette Islands Reserve is safe to eat and safe to sell commercially.